Environment
“I am grateful for public television’s courageous stand”
The host of "The UltraMind Solution" responds to Salon's critical article of his PBS medical special.
The value of public television consists in its independent and often farsighted advocacy for ideas and information that elevate the public consciousness, lighten the heart and inspire the mind. Dr. Robert Burton’s Salon article, “PBS’s latest infomercial,” does a disservice by discrediting public television while ignoring shifts in scientific research on systems biology and medicine that hold the promise of solving the puzzle of chronic disease and relieving suffering for millions.
All new ideas encounter challenge and opposition. As Einstein astutely noted, “Great spirits often encounter violent opposition from mediocre minds.” Paradigms don’t shift quietly in the night. A true scientist seeks to understand and inquire into the nature of phenomena. Unfortunately, Dr. Burton seeks to discredit and destroy without an attempt to understand.
Dr. Burton is steeped in 20th-century ideas of reductionist medicine — concepts that no longer represent the fundamental understanding of biological laws and principles emerging in the genomic era. Rather than just describe the phenomena we observe and call by the name of disease, we are able to reframe what we see by mechanisms and cause, not symptoms. The separate specialty disciplines such as neurology or psychiatry describe and treat disease based on disease categories that are no longer relevant as we understand the underlying mechanisms and causes of those diseases.
As the director of the National Institutes of Mental Health, Thomas Insel, M.D., said to me, the “DMS IV” (the psychiatric diagnostic bible) has 100 percent accuracy but 0 percent validity. What he means is simple — the names we have for diseases help us describe groups of people with common symptoms, but tell us nothing about the fundamental mechanisms of, causes of or right treatments for those “diseases.”
Clearly I recognize the magnitude of suffering from mental illness, cognitive and behavioral problems and the burden suffered by so many. That is why I wrote “The UltraMind Solution” and created the companion public television special, to bring forth emerging science in a way that can be understood and acted upon by the public at large. Every statement or claim in the book (and the public television special) is supported by numerous scientific references (attached here).
Through explaining the new paradigm or model of systems medicine in lay terms, I sought to empower individuals to take advantage of emerging science to address the fundamental causes of their suffering. The role of lifestyle, nutrition and environmental toxins on mood and cognitive disorders is undisputed and overwhelming.
The concepts and science outlined in the show and the book are founded in research being done at the National Institutes of Health’s New Road Map Initiative on Systems Medicine, and were recently the topic for a summit of 600 leaders, scientists and educators in this field at the Institute of Medicine held at the National Academy of Sciences. I also recently was invited to testify on functional medicine (Applied Clinical Systems Medicine) before the Senate working group on healthcare reform and met with key officials in the White House. We are beginning a major research program in this field at one of the world’s leading medical institutions, the details of which will be finalized and announced within the next few months.
Rather than disregard present medical knowledge and research, as Dr. Burton suggests I do in my work, I seek to bring it front and center, not “cherry-pick” the research. Across every medical discipline and specialty, the role of inflammation is clear and beyond dispute. Cardiovascular disease, cancer, obesity, osteoporosis, depression, Alzheimer’s and autism as well as asthma, allergies and autoimmune disease are among the many chronic diseases linked by common underlying mechanisms including inflammation. The data is overwhelming. Unfortunately the “mainstream medical wisdom” that Dr. Burton seeks to protect often no longer reflects the emerging science. Clearly Dr. Burton has not reviewed the nearly 500 scientific references (quite a lot of cherries) in my book that link a few underlying mechanisms to nearly all chronic diseases.
He also seeks to distort and discredit scientific information. Dr. Martha Herbert has demonstrated larger brains of autistic children on MRIs and has linked those to inflammatory changes documented by Dr. Vargas. She is a personal colleague, friend and research collaborator. Her work overwhelmingly has linked immune dysfunction and inflammation to the enlarged brains of autistic children.
Note to Dr. Burton: Immune dysfunction, and diffuse inflammation in the brains of autistic children, is the cause of the swollen brains.
Confusingly, Dr. Burton contradicts himself, simply pointing out that there appears to be inflammation in brains of autistic children but not signs of inflammation in the circulation, so the brain inflammation is therefore irrelevant. That is certainly not the conclusion of Dr. Vargas. In her landmark paper, “Neuroglial activation and neuroinflammation in the brain of patients with autism,” she says:
We demonstrate an active neuroinflammatory process in the cerebral cortex, white matter, and notably in cerebellum of autistic patients. Spinal fluid (CSF) showed a unique proinflammatory profile of cytokines [inflammatory proteins] … Our findings indicate that innate neuroimmune reactions play a pathogenic role in an undefined proportion of autistic patients.
Note to Dr. Burton: Pathogenic (disease causing) role, not “association,” is what the research findings of Dr. Vargas shows.
In a surprising distortion of the basic thesis of systems biology, Dr. Burton suggests I say that inflammation is the cause of dementia, depression or autism. I never state that inflammation is the “cause” but the mechanism common to so many chronic diseases. The causes are myriad, including poor diet high in sugar and trans fats and processed foods, infections, allergens, toxins and stress. Those create disease and pathology through the mechanism of inflammation. Addressing those causes and modulating inflammation through diet, lifestyle and environmental modifications is how the doctors of the future will practice medicine. Hopefully the future will not be too far off. This is the model of science and medicine that is the foundation of the show, my book and the field of functional medicine. But what is functional medicine?
Functional medicine is not a unique and separate body of knowledge, but it does represent a different way of applying the scientific and clinical information that emerges from the research literature and from the clinical practices of many disciplines. It is a way of thinking about disease based on how all the body’s systems work together. It helps doctors find the cause and understand the mechanism instead of just treat symptoms while the underlying disease process continues.
Change does not come easy, and will certainly incite ardent detractors. It may be helpful to remember Schopenhauer’s words: “All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.”
I am grateful for public television’s courageous stand for what is right, however difficult that may be.
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Robert Burton responds here.
Is it ethical to drive stick?
More drivers are buying manual transmissions -- a boon for auto sentimentalists but bad news for the environment
(Credit: cristapper via Shutterstock) Ever since I first watched my dad drive his chocolate brown Datsun 280 ZX back in the early 1980s, I’ve been inculcated to believe that driving — true driving — can only be performed with a stick shift. From that childhood experience, I came to see the manual transmission as a birthright passed down from my grandfather, to my father, and eventually to me via a series of tense, stall-filled lessons when I turned 16. In my case, after ripping apart the transmission one too many times, my dad went barking drill sergeant on me, eventually teaching me that a stick requires a special kind of focus, and that I needed to ease up more slowly on the clutch in order to get into first gear on those damn inclines. Through the experience, I learned to consider my stick-shifting skill a special talent with transcendent value.
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David Sirota is a best-selling author of the new book "Back to Our Future: How the 1980s Explain the World We Live In Now." He hosts the morning show on AM760 in Colorado. E-mail him at ds@davidsirota.com, follow him on Twitter @davidsirota or visit his website at www.davidsirota.com. More David Sirota.
An eco-pioneer’s final words
The visionary author of "Ecotopia," who died in April, warns of dark times ahead, but sees a path through the decay
To all brothers and sisters who hold the dream in their hearts of a future world in which humans and all other beings live in harmony and mutual support — a world of sustainability, stability, and confidence. A world something like the one I described, so long ago, in “Ecotopia” and “Ecotopia Emerging.”
As I survey my life, which is coming near its end, I want to set down a few thoughts that might be useful to those coming after. It will soon be time for me to give back to Gaia the nutrients that I have used during a long, busy and happy life. I am not bitter or resentful at the approaching end; I have been one of the extraordinarily lucky ones. So it behooves me here to gather together some thoughts and attitudes that may prove useful in the dark times we are facing: a century or more of exceedingly difficult times.
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Here’s the short version of humanity’s relationship with water, as delivered by hydrologist Jay Famiglietti in Jessica Yu’s compelling and often gorgeous documentary “Last Call at the Oasis”: “We’re screwed.” Yes, we should all install low-flush toilets and plant gardens that require less watering, but conservation is simply insufficient to cope with a global fresh-water crisis that involves many interlocking factors: overpopulation and overdevelopment, depletion of groundwater, climate change, and widespread contamination.
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After a year of freakish and destructive weather, Americans are finally waking up to the dangers of climate change
Houses were severely damaged after Hurricane Irene came through Bethel, Vt. on August 28, 2011 (Credit: U. S. Fish and Wildlife Service - Northeast Region / CC BY 2.0) The Williams River was so languid and lovely last Saturday morning that it was almost impossible to imagine the violence with which it must have been running on August 28, 2011. And yet the evidence was all around: sand piled high on its banks, trees still scattered as if by a giant’s fist, and most obvious of all, a utilitarian temporary bridge where for 140 years a graceful covered bridge had spanned the water.
The YouTube video of that bridge crashing into the raging river was Vermont’s iconic image from its worst disaster in memory, the record flooding that followed Hurricane Irene’s rampage through the state in August 2011. It claimed dozens of lives, as it cut more than a billion-dollar swath of destruction across the eastern United States.
Continue Reading CloseBill McKibben is the Schumann Distinguished Scholar at Middlebury College, and founder of the global climate campaign 350.org. His latest book is "Eaarth: Making a Life on a Tough New Planet.". More Bill McKibben.
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No, there's no new pro-necrophilia law in Egypt, and the EPA isn't "crucifying" all oil companies
The (now updated) Daily Mail story that launched the necrophilia myth (Credit: Daily Mail) Did you hear about the new law in Egypt that the Muslim Brotherhood supported that allowed people to have sex with dead women? It was on all the blogs yesterday. “Hard to come up with a more apt image of the Arab Spring than an aroused Islamist rogering a corpse,” wrote Mark Steyn. It’s hard to come up with a more apt image of the state of contemporary Islamophobia than Mark Steyn furiously pondering the image of “an aroused Islamist rogering a corpse.”
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Alex Pareene writes about politics for Salon and is the author of "The Rude Guide to Mitt." Email him at apareene@salon.com and follow him on Twitter @pareene More Alex Pareene.
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